Domestically-Produced Monoclonal-Antibody-Based Means of Diagnosing Particularly Dangerous Infections

Currently, great significance is attached to the preparation of diagnostic drugs based on specific immunoreagents, which include monoclonal antibodies produced by hybridomas. The use one important approaches for detection pathogens particularly dangerous infections – anthrax, brucellosis, tularemia, plague, cholera, glanders, and melioidosis. review presents main achievements Russian scientists obtaining such experimental drugs, also pays attention those sets reagents that are authorized in Federation. To date, three detecting causative agent anthrax (latex agglutination, immunochromatographic method, multiplex immunofluorescence analysis) have been registered our country basis antibodies; four identifying tularemia analysis, dot-variant enzyme immunoassay); plague microbe (enzyme immunoassay immune chromatographic tests); five cholera vibrios (slide immunofluorescence, method two diagnosis glanders melioidosis (immunofluorescence); kits brucella not registered, there only singular designs. involvement modern will improve quality reliability laboratory analysis.